Methods for the synthesis of 2-aminothiophenes and their reactions (review)

Autor: K. Gewald
Rok vydání: 1976
Předmět:
Zdroj: Chemistry of Heterocyclic Compounds. 12:1077-1090
ISSN: 1573-8353
0009-3122
DOI: 10.1007/bf00945583
Popis: 2-Aminothiophenes are readily formed as a result of various cyclization reactions. The method of preparation of derivatives of 2-aminothiophene-3-carboxylic acids and 2-amino-3-acylthiophenes from carbonyl compounds, nitriles that have an active methylene group, and sulfur is particularly simple and rich in possibilities. The aminothiophenes can be converted to other thiophene derivatives and used primarily for the preparation of condensed thiophenes such as thionaphthenes, thienopyrroles, thienothiazoles, thienoisothiazoles, thienopyrimidines, thienopyridines, and thienodiazepines.
Databáze: OpenAIRE