Methods for the synthesis of 2-aminothiophenes and their reactions (review)
Autor: | K. Gewald |
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Rok vydání: | 1976 |
Předmět: | |
Zdroj: | Chemistry of Heterocyclic Compounds. 12:1077-1090 |
ISSN: | 1573-8353 0009-3122 |
DOI: | 10.1007/bf00945583 |
Popis: | 2-Aminothiophenes are readily formed as a result of various cyclization reactions. The method of preparation of derivatives of 2-aminothiophene-3-carboxylic acids and 2-amino-3-acylthiophenes from carbonyl compounds, nitriles that have an active methylene group, and sulfur is particularly simple and rich in possibilities. The aminothiophenes can be converted to other thiophene derivatives and used primarily for the preparation of condensed thiophenes such as thionaphthenes, thienopyrroles, thienothiazoles, thienoisothiazoles, thienopyrimidines, thienopyridines, and thienodiazepines. |
Databáze: | OpenAIRE |
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