| Autor: |
Kap Ho Kim, Hyun Jung Yoo, Ki Hyun Gil, Joo-Young Lee, Ji Young Lee, Si Whan Song, Hyun Kul Lee, Su Jung Woo, Hu Song Zhang, Kwang Ho Kim, Zhong Ze Han, Jin Sook Bae, Tae Hwan Ahn, Chan Koo Park, Hong De Xu |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
Laboratory Animal Research. 26:153 |
| ISSN: |
1738-6055 |
| DOI: |
10.5625/lar.2010.26.2.153 |
| Popis: |
The purpose of this paper is to provide reference data related to the body weight, food & water consumptions, urinalysis, hematology and serum biochemistry parameters and absolute & relative organ weights obtained from control Sprague-Dawley rats, used in the 4-week and 13-week repeated-dose toxicity studies conducted in our laboratory between 2005 and 2008. The mean, standard deviation, minimum and maximum range values for hematology and serum biochemistry parameters, data of absolute & relative organ weights, and the difference between sexes and study duration of week 4 versus 13 week are presented. The studies were conducted according to “the standards of Toxicity Study for Medicinal Products” (2005) and The KFDA Notification No. 2000-63 ‘Good Laboratory Practice (GLP)’ (2000) issued by KFDA. These data could be used as reference material of Sprague-Dawley rats by conducting the studies to evaluate the toxicological profile of pre-clinical toxicity studies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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