Which laboratory malnutrition markers best predict 1-year mortality in hospitalized older adults?
| Autor: | Maias Abd-Elraheem, Noa Mashav, Dan Justo, Anjelika Kremer, Marina Ioffe |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
education.field_of_study medicine.medical_specialty 030214 geriatrics biology business.industry Population Serum albumin Albumin medicine.disease 03 medical and health sciences Malnutrition 0302 clinical medicine chemistry Transferrin Internal medicine Cohort biology.protein Vitamin D and neurology Medicine 030212 general & internal medicine education Prospective cohort study business |
| Zdroj: | European Geriatric Medicine. 10:619-624 |
| ISSN: | 1878-7657 |
| DOI: | 10.1007/s41999-019-00204-1 |
| Popis: | To study which laboratory malnutrition markers best predict 1-year mortality in hospitalized older adults as well as among patients at risk for malnutrition. Low albumin serum levels best predict 1-year mortality in hospitalized older adults as well as among patients at risk for malnutrition, followed by low transferrin serum levels. Together with low albumin serum levels, low transferrin serum levels also predict mortality in hospitalized older adults. To study which laboratory malnutrition markers best predict 1-year mortality in the general population of hospitalized older adults as well as among patients at risk for malnutrition. A historical prospective study. All older adults (age ≥ 65 years) hospitalized in one geriatric department during 9 months were included. Malnutrition Universal Screening Tool (MUST) was used to determine malnutrition risk. Laboratory malnutrition markers included albumin serum levels, transferrin serum levels, total cholesterol serum levels, vitamin D serum levels, and lymphocyte count. A receiver operating characteristic (ROC) curve analysis was used to study which markers best predict 1-year mortality. Overall, 437 patients (63.2% women; mean age 84.7 years) were included. Overall, 126 (28.8%) patients died in the year following admission. ROC curve analysis showed that low albumin serum levels best predict 1-year mortality (AUC 0.721, p |
| Databáze: | OpenAIRE |
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