Popis: |
Our initial discussions surrounding controlled-release systems focused on the fundamentals of composition, release, and diffusion [1]. Alterations to these three basic parameters led to distinct profiles that identified their potential areas of application, such as embolics [2] or gel caps [3]. We can recall from Chap. 1 that there are various routes we can either actively or passively enter the body. The general applications were restricted in our discussion in Chap. 2 to oral drug delivery, traditionally entering the bloodstream through hydrolysis in the stomach, or implantation, done at the site of treatment. Since drug delivery encompasses a broad spectrum of treatment methodologies, we can ask two basic questions |