Neurons with different neurotransmitters in embryonic neocortical allografts in the rat sciatic nerve
Autor: | Petrova Es |
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Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Catecholaminergic Pathology medicine.medical_specialty Neocortex Tyrosine hydroxylase Glutamate decarboxylase Anatomy Biology Choline acetyltransferase General Biochemistry Genetics and Molecular Biology gamma-Aminobutyric acid 03 medical and health sciences 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure nervous system medicine GABAergic Sciatic nerve General Agricultural and Biological Sciences 030217 neurology & neurosurgery medicine.drug |
Zdroj: | Biology Bulletin. 43:97-103 |
ISSN: | 1608-3059 1062-3590 |
Popis: | Different subsets of interneurons in the Wistar rat neocortex and in neocortical transplants developing in a damaged nerve were identified by the following immunohistochemical markers: glutamate decarboxylase (GAD 67) for GABAergic nerve cells, NO-synthase (NOS) for NO-ergic neurons, choline acetyltransferase (ChAT) for cholinergic cells, and tyrosine hydroxylase for catecholaminergic structures. Twenty-eight days after surgery, individual GAD 67-ir, NO-ir, ChAT-ir, and very rarely TH-ir cells were detected in the graft. It was shown that the number of GAD 67-ir neurons per unit area in the grafts was less than in the rat neocortex P20. |
Databáze: | OpenAIRE |
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