Bis(trifluoromethyl)-containing 1-azatricycloheptanes

Autor: G. A. Sokolsky, S. S. Khokhlov, V. M. Nagaev, A. F. Yeleyev
Rok vydání: 1998
Předmět:
Zdroj: Russian Chemical Bulletin. 47:134-138
ISSN: 1573-9171
1066-5285
DOI: 10.1007/bf02495520
Popis: 6-Substituted 7-halo-3,3-bis(trifluoromethyl)-2-azabicyclo[2.2.1]heptanes were synthesized by the addition of water, alcohols, and acetic acid to 3-halo-7,7-bis(trifluoromethyl)-1-azatricyclo[2.2.1.02,6]heptanes in the presence of H2SO4. 5,6-Disubstituted 3,3-bis(trifluoromethyl)-2-azabicyclo[2.2.1]heptanes were prepared by oxymercuration of 3,3-bis(trifluoromethyl)-2-azabicyclo[2.2.1]hept-5-ene.
Databáze: OpenAIRE