CHEl UF Serum Cholinesterase Phenotype in Whites and Non-Whites from Southern Brazil as Determined by a New Method

Autor:	Eleidi A. Chautard-Freire-Maia, Vânia M. Alcântara, L. Culpi
Rok vydání:	1991
Předmět:	Animal science Serum cholinesterase Genetics Population study Curitiba Biology Allele biology.organism_classification Phenotype Allele frequency Genetics (clinical)
Zdroj:	Human Heredity. 41:103-106
ISSN:	1423-0062 0001-5652
DOI:	10.1159/000153986
Popis:	A sample of 251 Whites and 818 Non-Whites, from Curitiba (southern Brazil), was typed with a new method with the aim of estimating the frequency of the CHE1*F allele. The frequency of this allele did not differ between Whites (0.60 ± 0.34%) and Non-Whites (0.49 ± 0.17%), being estimated as 0.51 ± 0.15% for the whole sample. The use of the inhibitors DL-propranolol and RO2–0683 with α-naphthylacetate as substrate (at 37°C) was efficient for discriminating between the CHE1 U and CHE1 UF phenotypes.
Databáze:	OpenAIRE
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