Highly potent anti-malarial activity of benzopyrano(4,3-b)benzopyran derivatives and in silico interaction analysis with putative target Plasmodium falciparum lactate dehydrogenase
| Autor: | Naresh Kumar, Rahul S. Hada, Juveria Khan, Nishant Joshi, Sonal Gupta, Jeremy C. Dobrowolski, Shailja Singh, Pawan K. Dhar |
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| Rok vydání: | 2021 |
| Předmět: |
0303 health sciences
Quantitative structure–activity relationship Anti malarial biology Chemistry In silico 030303 biophysics Plasmodium falciparum General Medicine medicine.disease biology.organism_classification Benzopyran 03 medical and health sciences chemistry.chemical_compound Docking (dog) Biochemistry Structural Biology Lactate dehydrogenase parasitic diseases medicine Molecular Biology Malaria |
| Zdroj: | Journal of Biomolecular Structure and Dynamics. 40:5159-5174 |
| ISSN: | 1538-0254 0739-1102 |
| Popis: | Malaria infection caused by Plasmodium falciparum is majorly responsible for millions of deaths in humans every year. Moreover, a rapid increase in resistance to existing drugs has posed an urgent ... |
| Databáze: | OpenAIRE |
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