Effect of asthma and PTSD on persistence and onset of gastroesophageal reflux symptoms among adults exposed to the September 11, 2001, terrorist attacks
| Autor: | James E. Cone, Jiehui Li, Mark R. Farfel, Robert M. Brackbill, Steven D. Stellman, Hannah T. Jordan |
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| Rok vydání: | 2016 |
| Předmět: |
Persistence (psychology)
medicine.medical_specialty business.industry fungi Public Health Environmental and Occupational Health Reflux World trade center Late onset medicine.disease Mental health 03 medical and health sciences Posttraumatic stress 0302 clinical medicine Epidemiology medicine 030211 gastroenterology & hepatology 030212 general & internal medicine Psychiatry business Asthma |
| Zdroj: | American Journal of Industrial Medicine. 59:805-814 |
| ISSN: | 0271-3586 |
| Popis: | Background Little is known about the direction of causality among asthma, posttraumatic stress disorder (PTSD), and onset of gastroesophageal reflux symptoms (GERS) after exposure to the 9/11/2001 World Trade Center (WTC) disaster. Methods Using data from the WTC Health Registry, we investigated the effects of early diagnosed post-9/11 asthma and PTSD on the late onset and persistence of GERS using log-binomial regression, and examined whether PTSD mediated the asthma-GERS association using structural equation modeling. Results Of 29,406 enrollees, 23% reported GERS at follow-up in 2011–2012. Early post-9/11 asthma and PTSD were each independently associated with both the persistence of GERS that was present at baseline and the development of GERS in persons without a prior history. PTSD mediated the association between early post-9/11 asthma and late-onset GERS. Conclusions Clinicians should assess patients with post-9/11 GERS for comorbid asthma and PTSD, and plan medical care for these conditions in an integrated fashion. Am. J. Ind. Med. 59:805–814, 2016. © 2016 Wiley Periodicals, Inc. |
| Databáze: | OpenAIRE |
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