Risk factors and outcome of hypertension in living related renal transplant recipients

Autor: C. K. Jacob, J. C. M. Shastry, M Rao, K Sud
Rok vydání: 1995
Předmět:
Zdroj: Nephrology. 1:535-539
ISSN: 1440-1797
1320-5358
DOI: 10.1111/j.1440-1797.1995.tb00052.x
Popis: Summary: Impaired allograft function is an important cause of hypertension in cadaveric renal transplant recipients. the risk factors for post-tranplant hypertension in living related transplant recipients with inherent good graft functions are likely to be different and have not been studied. In addition, controversy surrounds any independent effect hypertension might have on renal allograft functions. Four hundred and seventy three living related renal allograft recipients were retrospectively analysed to study the risk factors for development of post-transplant hypertension and its effect on graft outcome. Prevalence of hypertension was 76.1%. the presence of pre-transplantation hypertension was the most important independent risk factor for development of hypertension after transplantation. This suggests an important role of retained native diseased kidneys as a cause of hypertension. Other risk factors included: cyclosporin A immunosuppression, patient age less than 40 years and the presence of renal insufficiency at last follow up. Hypertension did not have any effect on patient or graft survival during the mean follow-up period of 20.1 ± 13.7 months; however, it was associated with an independent risk for the presence of renal insufficiency in the post-transplant period.
Databáze: OpenAIRE