| Popis: |
Twenty years ago, the child with severe haemophilia was not expected to survive beyond the fourth decade [1]. If he did he was likely to have marked haemophilic arthropathy, affecting hips and shoulders, knees, ankles and elbows. His arthritis would have crippled him, and, together with contractures due to fibrous repair following muscle haemorrhage, would have marked him out from his peers early in his adult life. He would have been less likely to marry [2] and less likely to succeed in his chosen career [3] than his non-haemophilic contemporaries. In short, unless he was lucky, he was denied both quantity and quality of life. |
