Distinctive HLA-A,B antigens of black populations formed by interallelic conversion

Autor:	J A Madrigal, M P Belich, W H Hildebrand, R J Benjamin, A M Little, J Zemmour, P D Ennis, F E Ward, M L Petzl-Erler, E D du Toit
Rok vydání:	1992
Předmět:	Immunology Immunology and Allergy
Zdroj:	The Journal of Immunology. 149:3411-3415
ISSN:	1550-6606 0022-1767
Popis:	Alleles encoding five HLA-A and B Ag characteristic of black populations have been isolated and their nucleotide sequences determined. In each case, the "black" allele is similar to a "related" allele found in caucasoid populations. The primary differences between these pairs of alleles are localized clusters of nucleotide substitutions that change two to five residues of the Ag recognition site. The pattern of differences indicates that the pairs of black and caucasoid alleles diverged primarily as a result of interallelic conversion events.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::82115a3ec2dad239571d001749177330 https://doi.org/10.4049/jimmunol.149.10.3411 Zobrazit plný text záznamu