Popis: |
The effects of high pressure (400–600 MPa) and moderate heat (60–80 °C) treatments at various process times (10–20 min) on the reduction of Bacillus cereus As 1.1846 spores, suspended in milk buffer were investigated. In the present work, response surface methodology (RSM) was employed, and a quadratic equation of high hydrostatic pressure inactivation was built with RSM. By analyzing response surface plots and corresponding contour plots and by solving the quadratic equation, experimental values were shown to be significantly in agreement with predicted values, since the adjusted determination coefficient ( R Adj 2 ) was 0.9752 and the level of significance was P |