Neuromuscular blocking effects of certain antibacterial agents in pigs and lambs

Autor:	Babu P. Mathew, Jean A. Robinson, H.Richard Adams, Richard H. Teske
Rok vydání:	1978
Předmět:	Pharmacology General Veterinary Side effect Blocking (radio) Tetracycline Chloramphenicol Neomycin Biology Gastrocnemius muscle Antibiotic Agents Streptomycin Anesthesia medicine medicine.drug
Zdroj:	Journal of Veterinary Pharmacology and Therapeutics. 1:171-175
ISSN:	1365-2885 0140-7783
DOI:	10.1111/j.1365-2885.1978.tb00322.x
Popis:	The neuromuscular blocking effects of several antibacterial agents were examined in young pigs and lambs using a sciatic nerve-gastrocnemius muscle preparation. Intravenous administration of streptomycin, neomycin or tetracycline produced a decrease in indirectly stimulated contractions of the gastrocnemius muscle; whereas, chloramphenicol, sulphadiazine and penicillin-G had no discernible neuromuscular blocking effects. Present findings confirm the neuromuscular blocking activity of certain antibiotic agents, and indicate the potential for this adverse side effect in food-producing animal species.
Databáze:	OpenAIRE
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