Splenic lesion mimicking breast metastasis: The first description of splenic parenchymal endometriosis
| Autor: | Claire Illac, E. Cuellar, Elodie Chantalat, Marie-Charlotte Delchier, Ariane Weyl, Bertrand Suc |
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| Rok vydání: | 2020 |
| Předmět: |
Splenic lesion
Pathology medicine.medical_specialty 030219 obstetrics & reproductive medicine Extrapelvic endometriosis medicine.diagnostic_test business.industry Endometriosis Breast metastasis medicine.disease 03 medical and health sciences 0302 clinical medicine Positron emission tomography 030220 oncology & carcinogenesis Parenchyma medicine business |
| Zdroj: | Journal of Endometriosis and Pelvic Pain Disorders. 13:69-73 |
| ISSN: | 2284-0273 2284-0265 |
| Popis: | Introduction: Splenic parenchymal endometriosis has never been described to date. We report here the case of real parenchymal endometriosis of the spleen. Case description: In this case, a 54-year-old female patient presented a histologically proven metastatic recurrence of breast cancer in the internal breast chain. The CT-scan also detected a large cystic structure developed from the spleen, but non-suspected to be metastasis. The patient was treated with chemotherapy (paclitaxel) and a combination of targeted therapies (everolimus and trastuzumab). While a complete radiological and biological response was noted at 2 months, the splenic cyst gradually decreased over the years. When targeted therapies were stopped, a reincrease of the splenic lesion and de novo significant hypermetabolism of the splenic parenchyma on 18F-FDG PET scan were observed. A splenectomy was finally performed and revealed splenic parenchymal endometriosis. Conclusion: This case once again highlights the complexity of endometriosis disease, from a pathophysiological point of view, but also the difficulties of radiological characterisation, and diagnostic management. |
| Databáze: | OpenAIRE |
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