Physiological Daily Inhalation Rates for Free-Living Pregnant and Lactating Adolescents and Women Aged 11 to 55 Years, Using Data from Doubly Labeled Water Measurements for Use in Health Risk Assessment

Autor: Jules Brodeur, Jean-François Ducré-Robitaille, Pierre Brochu
Rok vydání: 2006
Předmět:
Zdroj: Human and Ecological Risk Assessment: An International Journal. 12:702-735
ISSN: 1549-7860
1080-7039
Popis: The distribution of physiological daily inhalation rates for pregnant and lactating females aged 11 to 55 years was determined according to total daily energy expenditures, energy costs for growth, pregnancy and lactation (maternal milk-energy synthesis and breast-energy output) in free-living females. Such published data were obtained using a methodology based on the disappearance rates of predetermined doses of doubly labeled water (2H2O and H2 18O) in urine from non-pregnant and non-lactating females (n = 357), as well as saliva from gravid and breastfeeding females (n = 91), monitored by gas-isotope-ratio mass spectrometry over an aggregate period of about 6,000 days. Monte Carlo simulations were necessary to integrate total daily energy requirements of non-pregnant and non-lactating females into energy costs and weight changes at the 9th, 22nd, and 36th week of pregnancy and at the 6th and 27th, postpartum week: 540,000 data were simulated. The present article confirms that physiological dai...
Databáze: OpenAIRE