ChemInform Abstract: Synthesis of 2-Acyltetrahydroisoquinolines and 2-Acyl-1,2,3,4-tetrahydro-1,2-benzothiazine-1,1-diones by Electrophilic Substitution Reactions of N-Acyl-2-phenylethylamines

Autor:	L. K. Lukanov, Atanas P. Venkov
Rok vydání:	2010
Předmět:	Electrophilic substitution chemistry.chemical_compound chemistry Electrophile General Medicine Benzothiazine Ring (chemistry) Chlorosulfonic acid Medicinal chemistry
Zdroj:	ChemInform. 29
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199842149
Popis:	1-Substituted- 5, 1,5-substituted 7,8-dioxygenated-2-acyltetrahydroisoquino-lines 10 and 2-acyl-1,2,3,4-tetrahydro-1,2-benzothiazine-1,1-diones 12 has been obtained by the reaction of N-acyl-2-phenylethylamines with aldehydes or chlorosulfonic acid as a result of an electrophilic hydroxyalkylation and chlorosulfonation of the aromatic ring.
Databáze:	OpenAIRE
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