Comparison of Five Detection Methods for Helicobacter pylori
| Autor: | Omer Senturk, Nadir Paksoy, Altay Celebi, Saadettin Hulagu, Nuh Zafer Cantürk, Cengiz Erçin, Zeynep Cantürk |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
medicine.medical_specialty
Histology medicine.diagnostic_test biology business.industry Spirillaceae Concordance General Medicine Helicobacter pylori biology.organism_classification Gastroenterology Pathology and Forensic Medicine law.invention Gram staining law Cytopathology Internal medicine Cytology Biopsy medicine Gastritis medicine.symptom business |
| Zdroj: | Acta Cytologica. 44:1010-1014 |
| ISSN: | 1938-2650 0001-5547 |
| DOI: | 10.1159/000328589 |
| Popis: | OBJECTIVE: To evaluate which diagnostic test is preferable for the diagnosis of Helicobacter pylori in patients with gastroduodenal disease. STUDY DESIGN: H pylori infection was diagnosed prospectively in 101 patients. Diagnosis of H pylori was made by tests based on five different principles: (1) culture, (2) direct histologic demonstration, (3) imprint cytology, (4) brushing cytology, and (5) gram staining of H pylori. Efficacy of each test was compared. RESULTS: All the tests were reliable for diagnosing H pylori infection; 73.3% of patients showed concordance in at least two tests. All the tests were positive in > 50% of patients. Significant concordance between brushing and imprint cytology was also determined. These two tests have almost similar specificity when compared to other tests. CONCLUSION: When patients undergo upper endoscopy, we recommend taking biopsy specimens for culture and histology. H pylori can be assessed equally well with all the tests, but imprint and brushing cytology have the advantage of rapid response, specificity, much lower cost and reproducibility. |
| Databáze: | OpenAIRE |
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