Clinical features and laboratory diagnosis of emerging arthropod-transmitted viruses

Autor: Eleanor A. Powell, Meghan W. Starolis, Omar Perez
Rok vydání: 2020
Předmět:
Zdroj: Journal of Clinical Virology. 132:104651
ISSN: 1386-6532
DOI: 10.1016/j.jcv.2020.104651
Popis: Arthropod-borne viruses (arboviruses) are an increasing global threat due to their ability to cause human disease and their expanding geographical distribution. They circulate in nature between arthropod vectors and vertebrate hosts. Infection of susceptible human hosts leads to harmful developmental and neurological manifestations. Arboviruses have caused recent outbreaks with significant public health implications, such as the Zika virus outbreak in the western hemisphere which caused fetal abnormalities in some infected pregnant women, or Eastern Equine Encephalitis which caused 15 deaths in 2019. This review discusses several arboviral infections and their clinical manifestations while highlighting the importance of laboratory diagnostics to detect infections and current attempts at vaccine development. The ability to accurately diagnose an arbovirus infection is critical for initiating a timely response to infections in order to improve patient outcomes.
Databáze: OpenAIRE