Dual energy iodine contrast CT with monochromatic X-rays

Autor: L. Perna, D. Greenberg, Dean Chapman, D.J. Krus, F. Giron, F.A. Dilmanian, M.H. Miller, J. Kress, Jeffrey A. Coderre, C.T. Roque, Daniel N. Slatkin, E C Parsons, William Thomlinson, K. Yamamoto, Terry M. Button, X. Y. Wu, M. Shleifer, H. Weedon, B. Ren, J. Liang, Zhong Zhong, M.J. Petersen
Rok vydání: 2002
Předmět:
Zdroj: 1995 IEEE Nuclear Science Symposium and Medical Imaging Conference Record.
DOI: 10.1109/nssmic.1995.500262
Popis: Computed tomography (CT) with monochromatic X-ray beams was used to image phantoms and a live rabbit using the preclinical multiple energy computed tomography (MECT) system at the National Synchrotron Light Source. MECT has a horizontal fan beam with a subject apparatus rotating about a vertical axis. Images were obtained at 43 keV for single-energy studies, and at energies immediately below and above the 33.17 keV iodine K-edge for dual-energy subtraction CT. Two CdWO/sub 4/-photodiode array detectors were used. The high-resolution detector (0.5 mm pitch, uncollimated) provided 14 line pair/cm in-plane spatial resolution, with lower image noise than conventional CT. Images with the low-resolution detector (1.844-mm pitch, collimated to 0.922 mm detector elements) had a sensitivity for iodine of /spl ap/60 /spl mu/g/cc in 11-mm channels inside a 135 mm-diameter acrylic cylindrical phantom for a slice height of 2.5 mm and a surface dose of /spl ap/4 cGy. The image noise was /spl ap/1 Hounsfield Unit (HU); it was /spl ap/3 HU for the same phantom imaged with conventional CT at approximately the same dose, slice height, and spatial resolution (/spl ap/7 1p/cm). These results show the potential advantage of MECT, despite present technical limitations.
Databáze: OpenAIRE