Characterization and Inhibitory Activity of Lactobacillus plantarum MG989 and Lactobacillus fermentum MG901 Isolated from Vaginal Microbiota of Korean Women against Gardnerella vaginalis and Candida albicans
| Autor: | 백남수 ( Nam-soo Paek ), 강창호 ( Chang-ho Kang ), 한설화 ( Seul Hwa Han ) |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Trichomoniasis biology Lactobacillus fermentum 030106 microbiology food and beverages biology.organism_classification medicine.disease medicine.disease_cause Corpus albicans Microbiology 03 medical and health sciences 030104 developmental biology Lactobacillus medicine Gardnerella vaginalis Bacterial vaginosis Candida albicans Vaginitis |
| Zdroj: | KSBB Journal. 31:40-45 |
| ISSN: | 1225-7117 |
| DOI: | 10.7841/ksbbj.2016.31.1.40 |
| Popis: | Vaginitis, also known as vaginal infection and vulvovaginitis, is an inflammation of the vagina and possibly vulva. The three main kinds of vaginitis are bacterial vaginosis, vaginal candidiasis, and trichomoniasis. The purpose of this study was to characterize Lactobacillus plantarum MG989 and L. fermentum MG901 isolated from the vaginas of healthy Korean women in terms of their inhibitory activity against the vaginitis associated pathogens such as Gardnerella vaginalis and Candida albicans. Co-culture experiments showed that the two Lactobacillus strains MG989 and MG901 significantly reduced the viability of G. vaginalis and C. albicans. Also, the two strains were resistant to bile acid up to 1% and their autoaggregation rates were as high as 83.33%. Further studies are underway to demonstrate that the two strains can be applied as pharmaceutical agents for recovering healthy vaginal ecosystem. |
| Databáze: | OpenAIRE |
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