Comparative Evaluation of QuEChERS Method Coupled to DLLME Extraction for the Analysis of Multiresidue Pesticides in Vegetables and Fruits by Gas Chromatography-Mass Spectrometry

Autor: Satyajeet Rai, Mohana Krishna Reddy Mudiam, Mohammed Haris Siddiqui, Abhishek Kumar Singh, Sapna Yadav, Anshuman Srivastava
Rok vydání: 2016
Předmět:
Zdroj: Food Analytical Methods. 9:2656-2669
ISSN: 1936-976X
1936-9751
DOI: 10.1007/s12161-016-0445-2
Popis: An economical and rapid multiresidue method has been developed using quick, easy, cheap, effective, rugged and safe (QuEChERS) procedure combined with dispersive liquid-liquid microextraction (DLLME) for the quantitative determination of 36 multiclass, multiresidue pesticides (13 organochlorines, 11 organophosphates, and 12 synthetic pyrethroids) in different vegetables and fruits without primary and secondary amine (PSA) cleanup step followed by gas chromatography-mass spectrometry (GC-MS) analysis. The procedure mainly involves the acetonitrile extraction in the presence of anhydrous MgSO4 and NaCl followed by DLLME using carbon tetrachloride (extraction solvent) and acetonitrile (disperser solvent). Experimental parameters were optimized using design of experiments (DoE) approach. The method developed without PSA cleanup step has yield similar analytical performance with that of method with PSA cleanup step for all the pesticides analyzed. The precision of the developed method was found to be less than 12 % and limit of detection for all the analyzed pesticides was found to be in the range of 0.001–0.010 mg kg−1. This method was successfully applied in different fruits and vegetables and the recoveries were found to be in the range of 87–106 % at 0.05 mg kg−1 with an acceptable precision (
Databáze: OpenAIRE
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