Autor: |
Laurie S. Starkey, Michael E. Jung |
Rok vydání: |
1997 |
Předmět: |
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Zdroj: |
Tetrahedron. 53:8815-8824 |
ISSN: |
0040-4020 |
Popis: |
The novel dimeric amino acid isodityrosine 1 has been synthesized by a route which uses a new method of diaryl ether preparation. Nucleophilic addition of a protected tyrosine to cyclohexenone oxide and the Pd(0)-catalyzed coupling of an aryl iodide with a protected iodoalanine derivative are the key steps in this synthesis. This represents one of the first efficient syntheses of this molecule beginning with two naturally-occurring amino acids as inexpensive starting materials |
Databáze: |
OpenAIRE |
Externí odkaz: |
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