STUDY OF HEPATIC FUNCTION IN NEONATAL ASPHYXIA
| Autor: | M. K. S. Shaikh, Manoj Narayan Paliwal, Prachi Paliwal, Meena Varma, Swati Mulye |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Asphyxia
medicine.medical_specialty Fetus business.industry Ischemia Hypoxia (medical) medicine.disease digestive system Gastroenterology digestive system diseases Perinatal asphyxia Hepatic function medicine.anatomical_structure Anesthesia Internal medicine Placenta medicine medicine.symptom business Perfusion |
| Zdroj: | Journal of Evolution of Medical and Dental sciences. 2:5764-5767 |
| ISSN: | 2278-4802 2278-4748 |
| DOI: | 10.14260/jemds/1058 |
| Popis: | BACKGROUND/AIMS: Birth asphyxia occurs when a baby does not receive enough oxygen before, during or after birth .It is an insult to the fetus or newborn due to lack of oxygen (hypoxia) and /or a lack of perfusion (ischemia) to various organs. Fetus totally depends for its oxygen supply and other nutrients on the blood supplied through placenta. In any case, if blood supplied through placenta is hampered, it leads to asphyxial injury. We performed this study to determine the incidence of liver failure in birth asphyxia and to correlate the severity of hepatic disorder with asphyxia by estimating serum AST and ALT. MATERIAL AND METHODS: The study included 70 asphyxiated neonates and 50 healthy neonates as controls. Serum AST and ALT were estimated by IFCC method for Aspartate aminotransferase and IFCC method for Alanine aminotransferase respectively. RESULT: Serum AST and ALT were found significantly higher in asphyxiated babies compared to control groups (p |
| Databáze: | OpenAIRE |
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