Anesthesia with intramuscular administration of alfaxalone in Spanish ribbed newt (Pleurodeles waltl)
| Autor: | Matteo Oliveri, Vaclav Ceplecha, Zdenek Knotek, Eva Cermakova |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pleurodeles
0303 health sciences General Veterinary biology 040301 veterinary sciences business.industry Sedation Alfaxalone Induction time 04 agricultural and veterinary sciences biology.organism_classification 030308 mycology & parasitology 0403 veterinary science 03 medical and health sciences Recovery period Anesthesia Heart rate Anesthetic medicine Righting reflex medicine.symptom business medicine.drug |
| Zdroj: | Journal of Exotic Pet Medicine. 33:23-26 |
| ISSN: | 1557-5063 |
| DOI: | 10.1053/j.jepm.2020.01.003 |
| Popis: | The objective of this investigation was to assess the usefulness of three different doses of alfaxalone administered intramuscularly in amphibian species. Thirty-two healthy, adult (5–9 years old) captive Spanish ribbed newts (Pleurodeles waltl) were used. Alfaxalone at a dose of 15, 20, and 30 mg/kg was administered into the muscles of the front legs of each newt, with a 4-week washout period between trials. Heart rate and depth of sedation were assessed for each animal prior to the administration of anesthetic (T0), and at 2-minute intervals over the initial 20 minutes, then at 5-minute intervals over 60 minutes, and at 15-minute intervals until a full duration of 120 minutes for each trial. The average induction time was reduced with increasing doses. The recovery period was prolonged with increasing doses. Intramuscular administration of alfaxalone proved a feasible method for immobilization and sedation in Spanish ribbed newts and resulted in loss of both the escape reflex and righting reflex. |
| Databáze: | OpenAIRE |
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