Study of serum ferritin, serum uric acid and plasma malondialdehyde (MDA) levels in non-alcoholic fatty liver disease
| Autor: | Meena Varma, Haresingh Makwane, Rajesh Kumar Jha, Pawan Kumar Kare, Amita Parmar |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty business.industry Serum uric acid Fatty liver nutritional and metabolic diseases Disease medicine.disease Malondialdehyde Obesity 03 medical and health sciences chemistry.chemical_compound Liver disease 030104 developmental biology 0302 clinical medicine Endocrinology chemistry Internal medicine Diabetes mellitus medicine Uric acid 030211 gastroenterology & hepatology business |
| Zdroj: | International Journal of Biomedical and Advance Research. 7:169 |
| ISSN: | 2229-3809 2455-0558 |
| DOI: | 10.7439/ijbar.v7i4.3183 |
| Popis: | Background : Non-alcoholic fatty liver disease (NAFLD) is one of most important cause of fatty liver that may lead to end-stage liver disease. Various studies have reported that serum ferritin, serum uric acid and plasma malondialdehyde (MDA) levels are related to the development of NAFLD. Diabetes and obesity are the major risk factors which are associated with NAFLD. The aim of this study was assessment of serum ferritin, serum uric acid and plasma MDA levels in NAFLD patients with diabetes and with obesity. Materials and Methods : In the present study, total (n = 230) subjects were recruited for the study and divided in three groups. Group I; (n = 79) diagnosed cases of non-alcoholic fatty liver disease with diabetes, group II; (n = 91) diagnosed cases of non-alcoholic fatty liver disease with obesity patients and group III included (n = 80) healthy control subjects. Serum ferritin was measured by ELISA method. Estimation of serum uric acid was done by uricase peroxidase colorimetric method. Plasma MDA was estimated by spectrophotometric method. Results: The present study shown that serum ferritin, serum uric acid and plasma MDA levels were significantly increased (p |
| Databáze: | OpenAIRE |
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