Control in bioreactors showing gradients

Autor: G. Honderd, K. Ch. A. M. Luyben, S. R. Weijers
Rok vydání: 1990
Předmět:
Zdroj: Bioprocess Engineering. 5:225-230
ISSN: 1615-7605
0178-515X
DOI: 10.1007/bf00376229
Popis: In large-scale bioreactors gradients often occur as a result of non-ideal mixing. This phenomenon complicates design and control of large-scale bioreactors. Gradients in the oxygen concentration can be modeled with a two-compartment model of the liquid phase. Application of this model had been suggested for the control of the dissolved oxygen concentration with a batch gluconic acid fermentation process as the model system. The control system consists of a controller, an observer and a parameter estimator. In this work, the controller design is reconsidered and, in simulation experiments, the performance of the control system has been investigated. When the parameter values are known, the controller in combination with the observer works adequately. The parameter estimator, however, yields incorrect parameters, which are caused by a coupling between two parameters. This causes a deviation of the estimated states from the process states. The simulation results suggest that a priori knowledge of the parameters is required for application of the model for control and state estimation.
Databáze: OpenAIRE
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