Electroconvulsive Therapy Complicated by Insecticide Ingestion
| Autor: | Stewart Rb, Frost Ml, DeVane Cl, Ware Mr, Berger Jj |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Poison control medicine.disease Clonazepam Surgery Psychiatry and Mental health Muscle relaxation Electroconvulsive therapy Oral administration Methohexital Anesthesia medicine Pseudocholinesterase deficiency Ingestion Pharmacology (medical) business medicine.drug |
| Zdroj: | Journal of Clinical Psychopharmacology. 10:72 |
| ISSN: | 0271-0749 |
| DOI: | 10.1097/00004714-199002000-00028 |
| Popis: | The patient attempted suicide, first with a flurazepam overdose, then with clonazepam. Nine days prior to his admission with us, the patient attempted suicide by drinking dimpylate (Diazenon), a commonly available household insecticide, for which he was hospitalized. We chose to treat the patient with electroconvulsive therapy. After preoxygenation, in accordance with proscribed standards, a defasciculating dose of D-tubocurarine, 3 mg was given intravenously followed by methohexital 60 mg and succinylcholine, 120 mg, given intravenously 2 minutes later. Assisted ventilation was required for 1 hour before neuromuscular blockade was completely reversed. Because of the prolonged effect of succinylcholine, a pseudocholinesterase deficiency was suspected. It was concluded that the patient's prolonged response to succinylcholine resulted from the ingestion of dimpylate, which is a pseudocholinesterase inhibitor. For subsequent ECT treatments, the patient required only 20-30 mg of succinylcholine for adequate muscle relaxation. Serial measurements of pseudocholinesterase revealed an almost normal level, 6.8 IU/liter, by the time of discharge 3 weeks later |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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