Autor: |
Lev N. Sidorov, Oleg N. Kharybin, Alexander A. Zadorin, V. A. Ioutsi, Pavel A. Khavrel, N. S. Ovchinnikova, Eugenii N. Nikolaev, Marina A. Yurovskaya, Nikita M. Belov, Alexey A. Goryunkov |
Rok vydání: |
2010 |
Předmět: |
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Zdroj: |
Tetrahedron. 66:3037-3041 |
ISSN: |
0040-4020 |
Popis: |
An efficient method for the diastereoselective synthesis of 5-substituted 3,4-fulleroproline esters based on the lithium salt-assisted cycloaddition of azomethine ylides has been developed. A series of the fulleroproline esters containing either electron donating or electron withdrawing substituents was prepared with high yields and diastereoselectivities provided by the S-trans-configuration of ylide generated in situ from the corresponding Schiff base in the presence of a lithium salt and base. This method provides easy preparation of 3,4-fulleroproline derivatives suitable for fullerene-based peptide synthesis. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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