The electromeric effect in polar 1,2-elimination is a myth. A revised version and a Unified Rule for Elimination

Autor:	Alvard S. Arakelyan, Alexander A. Gevorkyan, Anthony F. Cockerill
Rok vydání:	1997
Předmět:	Reaction conditions Elimination reaction Theoretical physics Chemistry Organic Chemistry Drug Discovery Polar Regioselectivity Electromeric effect Biochemistry
Zdroj:	Tetrahedron. 53:7947-7956
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(97)00468-7
Popis:	The orientation rules for elimination reactions are discussed. Currently accepted explanations of the Saytzev eliminations and the exceptions to it which have been found, based on electromeric effects, are not soundly based. A Unified Rule for Elimination (URE) is proposed, by which the regioselectivity of eliminations can be explained for a wide range of substrates and reaction conditions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::814f962369f6197cde75bb503c76e8ec https://doi.org/10.1016/s0040-4020(97)00468-7 Zobrazit plný text záznamu Full Text from ScienceDirect