A one-pot, pseudo four-component synthesis of novel benzopyrano[2,3-b]pyridines under solvent-free conditions

Autor:	Mohsen Vaziri, Reza Razeghi, Abolfazl Olyaei
Rok vydání:	2013
Předmět:	chemistry.chemical_classification Solvent free Four component Organic Chemistry Biochemistry Aldehyde Catalysis chemistry.chemical_compound chemistry Drug Discovery Michael reaction Organic chemistry Molecule Knoevenagel condensation Malononitrile
Zdroj:	Tetrahedron Letters. 54:1963-1966
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2013.01.124
Popis:	A facile, one-pot, pseudo four-component catalyst- and solvent-free synthesis of novel benzopyrano[2,3- b ]pyridines is achieved by Michael addition of various naphthols to iminocoumarin derivatives obtained from Knoevenagel condensation of salicylaldehydes with malononitrile, which can be attacked by another molecule of malononitrile to afford the title products. The advantages of this procedure are mild reaction conditions, high yields of products, generality, short reaction times and operational simplicity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8148af344a88f36cf050565a310350e5 https://doi.org/10.1016/j.tetlet.2013.01.124 Zobrazit plný text záznamu Full Text from ScienceDirect