Effect of Goserlin Acetate and Oxidative Stress in Iraqi Women with Recurrenceof Endometriosis
| Autor: | Tamara Sami Naji, Kisma M. Turki, Salwa H. N. Al Rubae'i |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Coenzyme Q10
Vitamin medicine.medical_specialty 030219 obstetrics & reproductive medicine Vitamin C business.industry Endometriosis medicine.disease_cause medicine.disease 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology chemistry Internal medicine Medicine 030212 general & internal medicine business Luteinizing hormone Testosterone Oxidative stress Hormone |
| Zdroj: | IOSR Journal of Dental and Medical Sciences. 15:117-122 |
| ISSN: | 2279-0853 2279-0861 |
| DOI: | 10.9790/0853-15073117122 |
| Popis: | Although surgery is currently the treatment of choice for managing endometriosis, recurrence poses a formidable challenge. Goserlinacetateis one of the most widely used medical therapies of endometriosisto induce ovarian suppression. The aim of this study was to evaluate the effect of goserlin acetate treatment on the hormonal changes (Luteinizing Hormone (LH), Follicle Stimulating Hormones (FSH), Testosterone (Test.) and Estradiol (E2)),antioxidant status (A, E, β-carotene and C) vitamins, Coenzyme Q10 (CoQ10), uric acid (UA) and oxidative stress (MDA) in goserelintreated patients with endometriosis.Ninety women were participated in this study.Sixty women patients with endometriosiswere undergoing laparoscopy and treated with goserlin acetate included as patients group (G1), age range was between 25-46 years. Thirty healthy women were selected as the control group (G2) age range was between 23-45 years.Results revealed that there is the highly significant difference (P≤0.01) between G1 and G2 groups in sera (Test., E2, β-carotene, vitamin C, CoQ10, UA and MDA) levels. The results showed a significant higher (p |
| Databáze: | OpenAIRE |
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