Organocatalyzed Highly Diastereo- and Enantioselective Tandem Sulfa-Michael-Mannich Reaction of 2-Mercaptoquinoline-3-carbaldimines with Maleimides

Autor:	Chuchi Tang, Haibin Song, Lulu Wu, Youming Wang, Zhenghong Zhou, Liang-Fu Tang
Rok vydání:	2014
Předmět:	Chemistry Organic Chemistry Quinoline Enantioselective synthesis Catalysis Stereocenter Inorganic Chemistry chemistry.chemical_compound Organocatalysis Yield (chemistry) Michael reaction Organic chemistry Stereoselectivity Physical and Theoretical Chemistry Mannich reaction
Zdroj:	ChemCatChem. 6:649-654
ISSN:	1867-3880
DOI:	10.1002/cctc.201300993
Popis:	A highly diastereo- and enantioselective organocatalyzed domino sulfa-Michael–Mannich reaction of 2-mercaptoquinoline-3-carbaldimines with maleimides has been developed. This approach provides a convenient and efficient access to multifuntionalized tetracyclic quinoline derivatives with three contiguous stereocenters in high yield with excellent stereoselectivity (up to >99:1 dr and >99 % ee).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8116b1c078adebe17f45317b9a29e902 https://doi.org/10.1002/cctc.201300993 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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