Correlation Depending on Age Between Saliva and Plasma Parameters

Autor: Daniela-Gabriela Bălan, Adelaida Avino, Daniela-Elena Gheoca Mutu, Alexandra Gaube, Alexandra Neagu, Raluca Tulin, Sebastian Isac, Dragoș Eugen Georgescu, Dorin Dragoș, Claudia Cobilinschi, Liviu Vasile Chiperi, Dorin Ionescu, Andra-Elena Balcangiu-Stroescu, Amalia Loredana Călinoiu, Ileana Adela Văcăroiu
Rok vydání: 2022
Předmět:
Zdroj: Internal Medicine. 19:27-35
ISSN: 1220-5818
Popis: Introduction. Because of the increasing interest in the study of saliva, many methods have become available that can allow us to perform multiple and rapid analyzes of the composition of salivary secretion using advanced techniques of nanotechnology and fluid micro- engineering. The objectives of our study were to identify immunoglobulin levels variations with age. Materials and methods. We conducted an analysis to check the correlation between saliva and plasma parameters on 24 patients. The study population was divided into 2 groups based on age, with a cut-off at 35 years. The differences on the variables between two groups were evaluated by TTEST and CORREL. Results. Total plasma calcium, as well as ionic calcium have increased values in group 2, the increase being statistically significant (p =0.04) only for ionic calcium. Significant correlation of plasma and salivary values in the case of IgA / IgG ratio, and also a significant correlation of salivary and plasma concentrations for IgG were identified in our study. Conclusions. The correlation between plasma and salivary parameters is closely related to age and these can be used as markers for diagnosis and evaluation of various pathologies. Also, regarding women, salivary calcium and phosphate concentrations increase with age showing peak values around menopause.
Databáze: OpenAIRE