Long-Term Results of the RAPCO Trials
| Autor: | Brian F. Buxton, Philip A. Hayward, Jai Raman, Simon C. Moten, Alexander Rosalion, Ian Gordon, Siven Seevanayagam, George Matalanis, Umberto Benedetto, Mario Gaudino, David L. Hare, Jullien Gaer, Justin Negri, Masashi Komeda, Rinaldo Bellomo, Laurie Doolan, Larry McNicol, John Brennan, Robert Chan, David Clark, Ronald Dick, Anthony Dortimer, David Ecclestone, Omar Farouque, Dharsh Fernando, Mark Horrigan, Anthony Jackson, Leslie Oliver, Nilesh Mehta, Voltaire Nadurata, Nim Nadarajah, George Proimos, Michael Rowe, Ben Sia, Christopher Webb, Nagesh Anaveker, Peter Barlis, Paul Calafiore, Boniface Chan, John Cotroneo, Jennifer Johns, Elizabeth Jones, Paul Kertes, David O’Donnell, Stephen Sylviris, Anew Tonkin, Robert Fabini, Leighton Kearney, Ruth Lim, Maurice Molan, Gerard Smith, Chris Wellman, John Eng, Irbaz Hameed, Margaret Shaw, Sana Gerbo |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Heart disease business.industry Internal thoracic artery 030204 cardiovascular system & hematology medicine.disease 03 medical and health sciences 0302 clinical medicine Clinical research medicine.anatomical_structure Bypass surgery Physiology (medical) medicine.artery Internal medicine medicine Cardiology Vascular Patency 030212 general & internal medicine Radial artery Cardiology and Cardiovascular Medicine business Survival rate Artery |
| Zdroj: | Circulation. 142:1330-1338 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/circulationaha.119.045427 |
| Popis: | Background: An internal thoracic artery graft to the left anterior descending artery is standard in coronary bypass surgery, but controversy exists on the best second conduit. The RAPCO trials (Radial Artery Patency and Clinical Outcomes) were designed to compare the long-term patency of the radial artery (RA) with that of the right internal thoracic artery (RITA) and the saphenous vein (SV). Methods: In RAPCO-RITA (the RITA versus RA arm of the RAPCO trial), 394 patients Results: In the RA versus RITA comparison, the estimated 10-year patency was 89% for RA versus 80% for free RITA (hazard ratio for graft failure, 0.45 [95% CI, 0.23–0.88]). Ten-year patient survival estimate was 90.9% in the RA arm versus 83.7% in the RITA arm (hazard ratio for mortality, 0.53 [95% CI, 0.30–0.95]). In the RA versus SV comparison, the estimated 10-year patency was 85% for the RA versus 71% for the SV (hazard ratio for graft failure, 0.40 [95% CI, 0.15–1.00]), and 10-year patient survival estimate was 72.6% for the RA group versus 65.2% for the SV group (hazard ratio for mortality, 0.76 [95% CI, 0.47–1.22]). Conclusions: The 10-year patency rate of the RA is significantly higher than that of the free RITA and better than that of the SV. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT00475488. |
| Databáze: | OpenAIRE |
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