Craniofacial Growth after Iatrogenic Cleft Palate Repair in a Fetal Ovine Model

Autor:	Alex Colburn, Sue Ann Thompson, John W. Canady
Rok vydání:	1997
Předmět:	Fetus medicine.medical_specialty business.industry Anatomy Surgery medicine.anatomical_structure Otorhinolaryngology Submucosa Cleft palate repair Medicine Gestation Oral Surgery Craniofacial Volume Pixel business Complication Craniofacial growth
Zdroj:	The Cleft Palate-Craniofacial Journal. 34:69-72
ISSN:	1545-1569 1055-6656
DOI:	10.1597/1545-1569(1997)034<0069:cgaicp>2.3.co;2
Popis:	Controversy exists over the impact of scar formation on craniofacial growth after cleft palate repair. The fetal ovine model presents an opportunity to study a group of animals with little or no scar using cephalometric studies of craniofacial growth after iatrogenic cleft palate repair. Grossly evident scar is formed in the palates of lambs repaired at 118 days or later in gestation, while those animals operated at 70 and 77 days' gestation exhibited no scar grossly and minimal scar histologically in the submucosa with normal nasal and oral mucosal surfaces. For this study, 15 lambs were studied: four were unoperated, three were operated at 70 days, one at 77 days, and seven had clefts produced and repaired at 118 to 133 days' gestation. The animals were euthanized at 1 month of age and the heads removed and frozen until analyzed. Computerized tomography of the heads was used to create voxel (volume pixel) data sets, and volume rendering and measurement software (Voxblast) was used to create a t...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::810919076401bc12dd3d741633858ba6 https://doi.org/10.1597/1545-1569(1997)034<0069:cgaicp>2.3.co Zobrazit plný text záznamu