Preparation of polymer-coated magnetite fine particles for immunoassay magnetic marker
| Autor: | Bongsoo Kim, Yeon-Sil Choi, Jung-Min Moon, Jang-Oo Lee, Kohji Yoshinaga, Tae Nakahara |
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| Rok vydání: | 2010 |
| Předmět: |
chemistry.chemical_classification
Materials science Polymers and Plastics General Chemical Engineering Organic Chemistry Composite number technology industry and agriculture macromolecular substances Polymer Macromonomer Polymer engineering chemistry.chemical_compound Monomer Adsorption chemistry Chemical engineering Materials Chemistry Copolymer Organic chemistry human activities Magnetite |
| Zdroj: | Macromolecular Research. 18:793-799 |
| ISSN: | 2092-7673 1598-5032 |
| DOI: | 10.1007/s13233-010-0803-7 |
| Popis: | Polymer-coated magnetite fine particles with carboxyl groups were developed for applications as an immunoassay magnetic marker. The magnetite composites were prepared using the following method. A hydrophilic macromer with a polymerizable vinyl group at the terminal was adsorbed on the surface of the magnetite fine particles. Subsequently, a hydrophilic vinyl monomer with a carboxyl group and a crosslinking agent were added to carry out a copolymerization reaction. The resulting magnetite composite particles were dispersed stably in an aqueous medium. The composite particles exhibited high antibody binding ability and high-sensitive magnetic properties suitable for applications as magnetic markers. |
| Databáze: | OpenAIRE |
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