Paraneoplastic Cerebellar Degeneration: A Rare but Important Consideration
| Autor: | Vikram V Holla, Prithvi Giri, Rakesh Shukla, Vinod Kumar Mehta |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Ataxia business.industry Advanced stage 030105 genetics & heredity Bioinformatics Malignancy medicine.disease Paraneoplastic cerebellar degeneration Occult 03 medical and health sciences 0302 clinical medicine nervous system medicine medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Clinical Case Reports. |
| ISSN: | 2165-7920 |
| DOI: | 10.4172/2165-7920.1000700 |
| Popis: | Paraneoplastic cerebellar degeneration is an uncommon autoimmune disorder characterized clinically by progressive, ultimately incapacitating ataxia and pathologically by destruction of cerebellar Purkinje cells, with variable loss of other cell populations. The paraneoplastic cerebellar degeneration can antedate the recognition of malignancy and hence can be a warning sign for occult tumor. We are reporting two cases of paraneoplastic cerebellar degeneration that presented before any evidence of tumor and later developed advanced stage of malignancy not amenable for surgery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|