Second Window Indocyanine Green (SWIG) Near Infrared Fluorescent Transventricular Biopsy of Pineal Tumor
| Autor: | Vivek P. Buch, Anna Cho, John Y K Lee, Steve S. Cho, Love Buch |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Third ventricle medicine.diagnostic_test business.industry Pineocytoma Endoscopic third ventriculostomy Transventricular medicine.disease Lesion 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine.anatomical_structure chemistry 030220 oncology & carcinogenesis Biopsy medicine Surgery Neurology (clinical) Radiology medicine.symptom Ependyma business Indocyanine green 030217 neurology & neurosurgery |
| Zdroj: | World Neurosurgery. 134:196-200 |
| ISSN: | 1878-8750 |
| Popis: | Background Second Window Indocyanine Green (SWIG) is a novel technique for real-time, intraoperative tumor visualization using a high-dose infusion of indocyanine green (ICG) 24 hours before surgery. Due to pathologic diversity found in the pineal region, tissue diagnosis in patients with pineal region mass is essential to optimize further clinical management. Case Description We present the case of a 75-year-old woman with known pineal region mass for 18 years, who presented with progressive classic signs and symptoms of obstructive hydrocephalus over the past 6 months. Preoperative imaging confirmed a contrast-enhancing pineal region tumor, which appeared to be obstructing the aqueduct of Sylvius, causing proximal obstructive hydrocephalus. We delivered 5 mg/kg of ICG intravenously 24 hours before the surgery. The patient underwent an endoscopic third ventriculostomy and a biopsy of the pineal lesion. The tumor demonstrated clear near-infrared fluorescence, which was distinct from surrounding third ventricle floor and ependyma. The signal-to-background ratio was 2.9. The final pathology report revealed a World Health Organization grade I pineocytoma. Conclusions We report on a novel application of near-infrared fluorescence for tumor identification of pineal region tumors, using the “SWIG technique.” |
| Databáze: | OpenAIRE |
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