Study of The Effect of Nutrition and Glycemic Control and on IGF-1 and Growth in Pre-pubertal Egyptian Children with T1DM
| Autor: | Nancy Samir El Barbary, Raef Malak Botros, Aliaa Ahmed Abdo El-Sherbeeny, Hanan Mahmoud Ali, Ala Muhammed Muhammed |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Percentile business.industry 030209 endocrinology & metabolism 030204 cardiovascular system & hematology medicine.disease Pediatric department 03 medical and health sciences 0302 clinical medicine Male patient Internal medicine Diabetes mellitus Female patient medicine Outpatient clinic In patient business Glycemic |
| Zdroj: | The Egyptian Journal of Hospital Medicine. 81:2084-2087 |
| ISSN: | 2090-7125 |
| Popis: | Background: Pre-Pubertal children who have T1DM are shorter than their non-diabetic peers. Objective: In the current study we aimed to evaluate the role of HbA1c and IGF-1 in these cases. Patients and Methods: The present study was a cross-sectional study conducted on 80 pre-pubertal Egyptian children: 30 males, 30 females with T1DM and 20 age-matched controls (10 males and 10 females), the participants were recruited from the Outpatient Clinic of the Pediatric Department of Ain Shams University Hospitals and the National Institute of Diabetes and Endocrinology in Cairo, Egypt during the period from July 2018 to January 2019. Results: The height and weight percentiles were found to be lower in type 1 diabetic children when compared to the controls with median values of 14.50 (IQR 27.98) in male patients, 17.95 (IQR 29.18) in female patients, and 87 (IQR 20.58) in the controls. A negative correlation between serum IGF-1 and HbA1c as well as the height and weight percentiles were found with (P = 0.014, 0.009, and 0.05 respectively). Serum IGF-1 levels were also found to be significantly lower in patients (P |
| Databáze: | OpenAIRE |
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