Use of Synthetic H Disaccharides as Acceptors for Detecting Activities of UDP-GalNAc:Fuc α1-->2Galβ-R α1-->3-N-Acetylgalactosaminyltransferase in Plasma Samples from Blood Group A Subgroups
| Autoři: | Rakesh K. Jain, C F Piscorz, Akira Takeya, N. Shimoda, Takashi Nakajima, H Ohi, Khushi L. Matta, Osamu Hosomi, T Tachikawa, Shin Yazawa |
|---|---|
| Zdroj: | Clinical Chemistry. 38:2392-2395 |
| Informace o vydavateli: | Oxford University Press (OUP), 1992. |
| Rok vydání: | 1992 |
| Témata: | chemistry.chemical_classification, Stereochemistry, Biochemistry (medical), Clinical Biochemistry, Alpha (ethology), Carbohydrate, Hexosaminidases, Red blood cell, Enzyme, medicine.anatomical_structure, chemistry, Biochemistry, ABO blood group system, Blood plasma, medicine, Beta (finance) |
| Popis: | Concentrations of blood group A-specified alpha(1-->3)-N-acetylgalactosaminyltransferase (A enzyme) were measured in human plasma of blood groups A1, A2, and A3 by using chemically synthesized H disaccharides and H type 1 and type 2 trisaccharides attached to hydrophobic aglycones as acceptors. When the trisaccharides were used as acceptors, enzyme activities were reduced in samples from A2 and A3. However, the H disaccharides were shown to be good acceptors even for enzymes from A2 and A3, and no significant difference in enzyme concentration was detected in any of the plasma tested. |
| ISSN: | 1530-8561 0009-9147 |
| DOI: | 10.1093/clinchem/38.12.2392 |
| Přístupová URL adresa: | https://explore.openaire.eu/search/publication?articleId=doi_________::80e77d34f90c8834cc6f597d4621cbba https://doi.org/10.1093/clinchem/38.12.2392 |
| Rights: | OPEN |
| Přírůstkové číslo: | edsair.doi...........80e77d34f90c8834cc6f597d4621cbba |
| Autor: | Rakesh K. Jain, C F Piscorz, Akira Takeya, N. Shimoda, Takashi Nakajima, H Ohi, Khushi L. Matta, Osamu Hosomi, T Tachikawa, Shin Yazawa |
| Rok vydání: | 1992 |
| Předmět: | |
| Zdroj: | Clinical Chemistry. 38:2392-2395 |
| ISSN: | 1530-8561 0009-9147 |
| DOI: | 10.1093/clinchem/38.12.2392 |
| Popis: | Concentrations of blood group A-specified alpha(1-->3)-N-acetylgalactosaminyltransferase (A enzyme) were measured in human plasma of blood groups A1, A2, and A3 by using chemically synthesized H disaccharides and H type 1 and type 2 trisaccharides attached to hydrophobic aglycones as acceptors. When the trisaccharides were used as acceptors, enzyme activities were reduced in samples from A2 and A3. However, the H disaccharides were shown to be good acceptors even for enzymes from A2 and A3, and no significant difference in enzyme concentration was detected in any of the plasma tested. |
| Databáze: | OpenAIRE |
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