Growth of Smooth Muscle Cell and Endothelial Cell on PLGA Film Containing EGCG
| Autor: | Hye Ryeon Lim, Hyun Sook Baek, Mi Hee Lee, Yeon I. Woo, Tek Hyung Lee, Jin Hyun Chung, Jeong Koo Kim, Seung Jin Lee, Jong Chul Park |
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| Rok vydání: | 2007 |
| Předmět: |
Scaffold
Materials science Cell growth Angiogenesis Mechanical Engineering Cell technology industry and agriculture food and beverages complex mixtures Endothelial stem cell PLGA chemistry.chemical_compound medicine.anatomical_structure chemistry Biochemistry Mechanics of Materials cardiovascular system medicine Biophysics General Materials Science Human umbilical vein endothelial cell sense organs Blood vessel |
| Zdroj: | Key Engineering Materials. :93-96 |
| ISSN: | 1662-9795 |
| DOI: | 10.4028/www.scientific.net/kem.342-343.93 |
| Popis: | Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested. |
| Databáze: | OpenAIRE |
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