IL-6 Levels Analysis Controlled in Type 2 Diabetes Mellitus Patients and Uncontrolled

Autor: Moonika Todingan, Rachmawati Muhiddin, Liong Boy Kurniawan
Rok vydání: 2023
Předmět:
Zdroj: INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY. 29:175-179
ISSN: 2477-4685
0854-4263
DOI: 10.24293/ijcpml.v29i2.1972
Popis: Interleukin 6 (IL-6) is one of the pro-inflammatory cytokines responsible for inducing tissue-specific and/or systemic inflammation, which is a major contributor to the induction of inflammation of pancreatic islet cells. Inflammation of pancreatic cells causes impaired insulin secretion and Type 2 Diabetes Mellitus (T2DM). This study aims to determine the levels of IL-6 in T2DM patients with different levels of severity. A cross-sectional study of 46 subjects was performed with 21 in the controlled T2DM group and 25 in the uncontrolled T2DM group. Interleukin-6 levels were measured using the ELISA method. The statistical tests used were the Mann-Whitney test and the Spearman test. The test results were significant if the p-value
Databáze: OpenAIRE