Synthesis and Antimicrobial Evaluation of New Monocyclic β-Lactams

Autor:	Jyotsna S. Meshram, Praveen Chidurala, Uppalaiah Kusampally, Ramakanth Pagadala, Himani N. Chopde, Venkateshwarlu Jetti
Rok vydání:	2012
Předmět:	Antifungal medicine.drug_class Chemistry Organic Chemistry β lactams medicine Antimicrobial Combinatorial chemistry Cycloaddition
Zdroj:	Journal of Heterocyclic Chemistry. 49:1151-1155
ISSN:	0022-152X
DOI:	10.1002/jhet.973
Popis:	A simple, practical, and efficient approach to synthesize new series of 2-(3-(2,4-dichlorophenoxy)-2-(4-(dimethylamino)phenyl)-4-oxoazetidin-1-ylamino)-N-arylacetamide by Staudinger [2 + 2] cycloaddition reaction. The titled compounds were evaluated for their antibacterial and antifungal activity against eight microorganisms. All the newly synthesized compounds are characterized by IR, 1H-NMR, and mass spectroscopic data.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::80c48f883d938fe5c11ac46e0d5aa4c0 https://doi.org/10.1002/jhet.973 Zobrazit plný text záznamu Plný text ve formátu PDF