Overriding effect of temperature over reagent and substrate size for boron-mediated aldol reaction of methyl phenylacetate
| Autor: | P. Veeraraghavan Ramachandran, Prem B. Chanda |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
chemistry.chemical_classification
Phenylacetates organic chemicals Methyl phenylacetate Organic Chemistry chemistry.chemical_element Substrate (chemistry) Biochemistry Medicinal chemistry chemistry.chemical_compound Aldol reaction chemistry Reagent Drug Discovery polycyclic compounds Alkoxy group Boron Alkyl |
| Zdroj: | Tetrahedron Letters. 54:5886-5888 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/j.tetlet.2013.08.106 |
| Popis: | The enolization temperature overrides all other aspects, including the sterics of the alkyl group of the boron reagent and the alkoxy group of the ester during the enolboration–aldolization of phenylacetates. This study has led to the first n -Bu 2 BOTf-mediated anti -selective aldol reaction of an ester. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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