Application of UHPLC and GC/MS for Detection of Hidden Drugs in Traditional Hand-Made Herbal Slimming Products
| Autor: | Tayebeh Tahamtan, Alireza Jahanbakhsh, Maryam Akhgari, Zahra Mousavi |
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| Rok vydání: | 2020 |
| Předmět: |
Active ingredient
food.ingredient Traditional medicine business.industry 04 agricultural and veterinary sciences 040401 food science 01 natural sciences 0104 chemical sciences 010404 medicinal & biomolecular chemistry 0404 agricultural biotechnology food Weight loss Herb medicine Herbal preparations General Pharmacology Toxicology and Pharmaceutics medicine.symptom Fast methods Gas chromatography–mass spectrometry business |
| Zdroj: | Jundishapur Journal of Natural Pharmaceutical Products. 15 |
| ISSN: | 2228-7876 1735-7780 |
| DOI: | 10.5812/jjnpp.82992 |
| Popis: | Background: Obesity is one of the health issues all over the world. Patients always demand convenient and fast methods for weight reduction. Hand-made herbal drugs are advertised by herbal practitioners to gain this goal. Unscrupulous manufacturers produce herbal products that are adulterated with hidden legal or illegal drugs to lose weight in a shorter period of time. Objectives: The main purpose of the present study was to analyze hand-made herbal slimming drugs to detect undeclared active pharmaceutical ingredients. Methods: Forty hand-made herbal products sold as weight loss aid were prepared from 270 herb shops in Gilan province, Iran, in a six-month period. All samples were analyzed using UHPLC and GC/MS instrumentations. Results: The results showed that 25% of collected herbal preparations contained caffeine. Moreover, an unlabeled herbal tablet contained metformin. Conclusions: Herbal slimming products in Gilan province were not adulterated as much as herbal drugs collected from other provinces in Iran. However, adulteration practices may endanger the health or safety of consumers. |
| Databáze: | OpenAIRE |
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