Sulfated Triterpenes from Lemon Balm
| Autor: | Suliman Y. Al Omar, Ahmed Idris, Khalid Z. Masoodi, Azra N. Kamili, Gulzar A. Bhat, Abdul S. Shawl, Bashir A. Ganai, Mudasir A. Tantry, Javid A. Dar |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Antioxidant
Traditional medicine Rosmarinic acid medicine.medical_treatment Organic Chemistry Antimicrobial Biochemistry Catalysis Inorganic Chemistry Terpene chemistry.chemical_compound Sulfation chemistry Drug Discovery Caffeic acid medicine Physical and Theoretical Chemistry Melissa officinalis Luteolin |
| Zdroj: | Helvetica Chimica Acta. 97:1497-1506 |
| ISSN: | 0018-019X |
| DOI: | 10.1002/hlca.201400001 |
| Popis: | The hydroalcoholic (EtOH/H2O) extract of matured leaf margins of lemon balm (Melissa officinalis L.) afforded a new 3,23-disulfate of 2α,3β-23,29-tetrahydroxyolean-12-en-28-oic acid 28-O-β-D-glucopyranoside (1) and a new 23-monosulfate of 2α,23-dihydroxyurs-12-en-28-oic acid 3-O-β-D-glucopyranoside (2), along with six known compounds, i.e., 23-monosulfate of 2α,3β,19α,23-tetrahydroxyurs-12-ene-28-oic acid 28-O-β-D-glucopyranoside (3), 3,5,6-trihydroxydehydro-α-ionol 9-O-β-D-glucopyranoside (4), quadranoside III (5), rosmarinic acid (6), caffeic acid (7), and luteolin (8). All the isolated compounds were evaluated for their antioxidant, antimicrobial, antimalarial, and cytotoxic activities. Only rosmarinic acid exhibited substantial antioxidant and antimicrobial activities, whereas sulfated terpenes showed considerably lower or no antimicrobial activity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|