Relations in Interferon Production and Other Known Properties between Cal 11914 and TCND Strains of Newcastle Disease Virus

Autor: Kaleta Ef, Bankowski Ra
Rok vydání: 1972
Předmět:
Zdroj: Avian Diseases. 16:481
ISSN: 0005-2086
DOI: 10.2307/1588663
Popis: Strain Cal 11914 of Newcastle disease virus (NDV) produced interferon (IF) in cultures of chick embryo fibroblast (CEF) as well as in chickens. The TCND strain of NDV did not produce IF in either system. IF titers reached a peak 4 hours after inoculation of CEF cultures, and IF was still detectable 18 hours later. In the chicken, IF titers reached a peak 2 hours after intravenous inoculation, and IF was still present 24 hours later, the longest period tested. The question was discussed of whether a strain of NDV used in a vaccine should be capable of producing IF.
Databáze: OpenAIRE