Lipid peroxidation parameters in the internal organs of rats with different degrees of resistance to hypoxia
| Autor: | V. M. Gukasov, M. L. Khachatur'yan, M. V. Bilenko, P. G. Komarov, L. B. Pirogova |
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| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Antioxidant Adult male medicine.medical_treatment General Medicine Biology Hypoxia (medical) General Biochemistry Genetics and Molecular Biology High resistance Lipid peroxidation chemistry.chemical_compound Endocrinology Acute hypoxia Biochemistry chemistry Internal medicine medicine medicine.symptom Low resistance |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 121:22-25 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | Lipid peroxidation and the antioxidant system of the heart, liver, and brain are studied in adult male Wistar rats with high and low resistance to hypoxia tested by “raising” to an altitude of 11.5 km and in intact outbred rats. These parameters are found to be the same in the brain of low- and high-resistance rats, while the brain content of lipid peroxidation products is higher in both groups of Wistar rats compared with outbred rats. The heart and liver parameters are coupled to the resistance to hypoxia. Antioxidant activity prevails over lipid peroxidation in the hearts and livers of high-resistance rats, confirming that oxidation plays a major role in the damaging and lethal effects of acute hypoxia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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