LCR-BLAST—A New Modification of BLAST to Search for Similar Low Complexity Regions in Protein Sequences

Autor: Patryk Jarnot, Marcin Grynberg, Aleksandra Gruca, Joanna Ziemska-Legięcka
Rok vydání: 2019
Předmět:
Zdroj: Advances in Intelligent Systems and Computing ISBN: 9783030319632
ICMMI
DOI: 10.1007/978-3-030-31964-9_16
Popis: Low Complexity Regions (LCRs) are fragments of protein sequences that are characterized by a small diversity in amino acid composition. LCRs could play important roles in protein functions or they could be relevant to protein structure. However, for many years, low complexity regions were ignored by the scientific community which resulted in lack of algorithms and tools that could be used to analyze this specific type of protein sequences.
Databáze: OpenAIRE